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SRI International Digest #14

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SRI International, an independent research institute, is helping meet important R&D challenges for our clients. In this quarterly edition of the Digest, learn about a DARPA-funded program that could save lives on the battlefield. Also read about our work to fight bioterrorism and breast cancer, and how we help clients build better products through microsystems innovations.

IN THIS ISSUE:

Trauma Pod Could Save Lives on the Battlefield

Imagine an automated medical treatment system that does not require onsite medical personnel on the front lines of battle that is ready to receive, assess, and stabilize wounded soldiers during the first critical hours following injury. The Defense Advanced Research Projects Agency (DARPA) has taken a significant step toward that goal by awarding a multi-organization team a $12 million, two-year contract to develop such a system. SRI, a pioneer in robotic surgery is the lead systems integrator for the program.

The groundbreaking program is an important step toward ensuring a future generation of battlefield-based unmanned medical treatment systems. These “trauma pods” could stabilize injured soldiers within minutes after a battlefield trauma and administer life-saving medical and surgical care prior to evacuation and during transport.

Read the Associated Press and San Francisco Chronicle articles for additional information.

Fighting Bioterrorism: SRI Part of $15 Million NIH Contract

With a goal of protecting U.S. citizens against the harmful effects of biological agents used in terrorism, biopharmaceutical company XOMA, Ltd. was recently awarded a $15 million, 18-month contract from the National Institute of Allergy and Infectious Diseases (NIAID). XOMA, which will produce three botulinum neurotoxin monoclonal antibodies, has selected SRI to develop the necessary potency assays to support antibody characterization. Read more information from XOMA.

Breast Cancer Research: SRI Models Cellular Networks

Under a new grant from the National Cancer Institute and the Lawrence Berkeley National Laboratory for the study of biological networks associated with cancer cell lines, SRI will develop a model of cellular signaling networks related to human breast cancer. SRI will apply Pathway Logic software, its novel approach to modeling biological entities and processes. The San Jose Mercury News covered the news.

Metabolic Pathways of "Rabbit Fever" Identified

Using a groundbreaking computational approach, SRI and collaborators have identified the predicted metabolic pathways of the bacterium that causes tularemia, or “rabbit fever” in animals and humans. An article about the findings is published in the February 2005 issue of Nature Genetics.

In related breakthrough, SRI researchers have performed a computational analysis of the human genome to predict metabolic pathways and new gene functions. Using SRI’s HumanCyc genome database, the analysis assigned 622 enzymes to roles in 135 predicted pathways. Scientists can use HumanCyc as a “power tool” to understand the genome in useful ways. Results are available on the HumanCyc website. An article about the findings was published in the December 22, 2004 edition of Genome Biology.

Industry Leader Walter Moos Joins SRI as VP of Biosciences

Walter H. Moos, Ph.D., has joined SRI as Vice President of the Biosciences Division. In this role, Dr. Moos will direct the institute's pharmaceutical and biotechnology discovery and development teams, which provide contract R&D services to government and commercial clients. Dr. Moos has more than 20 years of experience, and most recently served as chairman and CEO of MitoKor, Inc. Previously, he was a corporate VP at Chiron Corporation.

Computer Mouse Inventor Doug Engelbart Joins Hall of Fame

Douglas Engelbart, Ph.D., inventor of the computer mouse and other computing firsts while at SRI, has been named to the Silicon Valley Engineering Council Hall of Fame.

No Project Too Small for the MicroSystems Innovation Center

Under direction of Dr. Joseph Stetter, SRI's MicroSystems Innovation Center develops micro- and nanometer-scale structures, devices, and systems. The Center's design teams focus on real-world needs, including sensors for automotive and environmental applications; microdispensing and sample collection systems for biomedical and chemical environments; flat-panel displays and printers for consumer electronics; satellite ion thrusters for space technology; and microwave tubes and electronic optics. A new state-of-the-art facility on SRI's Menlo Park, CA campus houses the Center.

Meet SRI People

Meet Phil Harman, SRI's director of Congressional relations; Grace Chou, business development director; and Dan Humphrey, associate director of our Center for Education Policy.

SRI in the News

Military.com describes SRI’s role in the Phraselator, a handheld speech-based translation device used by soldiers for real-time language translation in overseas operations.

The San Francisco Chronicle includes SRI in a round-up of “research powerhouses” in the Bay Area.

Read more SRI news.

Upcoming Events

Cyber security: The Department of Homeland Security Cyber Security Research and Development Center will hold an invitation-only Emerging Security Technology Forum at SRI’s Arlington, Virginia office on April 13-14. Invited nformation security companies will present innovative technologies to defend against Distributed Denial of Service (DDoS) and worm attacks. Attendees will include government technologists, technical managers, and others responsible for purchasing new security technologies for cyber infrastructure. SRI manages the Center for the DHS.

Biosciences:
Learn about SRI's end-to-end drug discovery and drug development services at these upcoming events:

* American Association for Cancer Research annual meeting, Anaheim, CA, April 16-20
* BIO 2005, Philadelphia, June 19-22

CONTACT US

For more information on SRI's innovations and how we can help you, contact bizdev@sri.com. The SRI Digest welcomes your feedback. Please send suggestions or comments to newsletter@sri.com. Start or discontinue a subscription by sending an email to newsletter@sri.com.

 

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